Especially important to note are ACE inhibitors , narcotics, and Avandia rosiglitazone or Actos pioglitazone for diabetes. As with any prior significant medical problem, people who have had a drug use disorder or alcohol use disorder in the past should inform their healthcare provider. Because of the increased possibility of misuse of Lyrica in those individuals, closer monitoring may be necessary or another treatment may be preferable.
Lyrica should be taken at the prescribed dosage. If a dose of Lyrica is missed and it's almost time for the next dose, skip the missed dose. Two doses of Lyrica should not be taken together. Do not stop taking Lyrica without consulting your healthcare provider.
You should continue taking the drug even after experiencing pain relief. Also, plan for refills so that the prescription does not run out. People who are pregnant or plan to become pregnant should notify their healthcare provider before starting the drug. No adequate, well-controlled studies have been conducted in pregnant humans, and use is only appropriate when the potential benefit to the person who is pregnant outweighs the possible risk to the fetus.
Male fertility may also be impacted by taking Lyrica, so this should be discussed with your healthcare provider. Studies showed that the drug made male animals less fertile. Also, birth defects occurred in the offspring of male animals who were treated with pregabalin. Study results published in concluded that patients with sciatica improved to the same level whether given Lyrica pregabalin or placebo.
While the drug has been prescribed for various nerve-related conditions, including sciatica, some researchers do not recommend its use for sciatica based on the results. But, not all researchers agree—some think it may be useful for chronic sciatica. For certain, if you are currently taking Lyrica pregabalin , do not stop without consulting your healthcare provider first. Usually they're not severe.
Dosage recommendations vary depending on your condition and symptoms. Usually, though, healthcare providers start adults off with a low dose of milligrams mg per day of Lyrica, then may gradually increase it. The maximum dose is mg in a single day. Learn about treatment and lifestyle changes to cope with fibromyalgia and chronic fatigue syndrome.
Approval package for Lyrica. Approved December 30, Aspects of fibromyalgia in the general population: sex, pain threshold, and fibromyalgia symptoms. J Rheumatol. Lyrica [labeling].
Updated May Living with fibromyalgia, drugs approved to manage pain. Updated January 31, Pregnancy outcome following maternal exposure to pregabalin may call for concern. Although there is limited to no medical support for these claims, some people feel that there are natural alternatives for Lyrica including:.
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Health Conditions Discover Plan Connect. A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:. Call your doctor right away if you have an allergic reaction to Lyrica, as the reaction could become severe. Lyrica can cause weight gain in some people. Across clinical studies involving adults with different conditions:.
The researchers noted that the risk of weight gain from Lyrica appeared to be related to higher dosages and how long a person took the drug for. Lyrica may also cause swelling in your feet, hands, and legs, which can contribute to weight gain. Lyrica may cause sleepiness in some people. In clinical trials involving adults with different conditions:. Sleepiness was also reported in clinical trials of children taking Lyrica.
Because Lyrica can make you sleepy or dizzy, it can affect your ability to drive or operate machinery. For this reason, you should avoid these and other potentially dangerous activities until you know how Lyrica affects you. Talk with your doctor about when it may be safe for you to do these activities again. It was noted in clinical studies that some people experienced an increase or decrease in their libido sex drive while taking Lyrica. They can help determine the cause and discuss the best treatment for you.
Blurry vision could occur while taking Lyrica. Call your doctor if you experience any changes in your vision while taking Lyrica. Your doctor may decide to monitor your vision more frequently. Lyrica belongs to a class of medications called antiepileptic drugs AEDs. As with other AEDs, Lyrica may raise your risk for suicidal thoughts and behaviors. Lyrica may also increase your risk for new or worsening depression and other unusual changes in your behavior or mood.
But in clinical trials of people taking other AEDs:. If you have new or worsening depression or thoughts of suicide while taking Lyrica, talk with your doctor right away. They may recommend that you switch to a different medication to treat your condition. Your doctor may also recommend other ways to help lower your suicidal thoughts or behaviors.
Regardless of the condition that Lyrica is being used to treat, its manufacturer recommends adjusting the dosage for people with kidney problems. If you have kidney problems, talk with your doctor for more details. Typically, your doctor will start you on a low dosage. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. The following information describes dosages that are commonly used or recommended.
But be sure to take the dosage your doctor prescribes for you. The capsules are available in the following strengths:. Lyrica is also available as a liquid solution that you take by mouth. But this form of Lyrica is only available in one strength: 20 mg per milliliter.
The recommended starting dosage for diabetic nerve pain in adults is mg of Lyrica per day. This is taken as 50 mg three times per day. After 1 week, your doctor may increase your dosage to mg three times per day a total of mg per day. This is the maximum dosage for treating diabetic nerve pain. Your doctor will adjust your dosage as needed based on how well the drug is working for you and any side effects that you may experience.
For treating fibromyalgia in adults, the recommended starting dosage of Lyrica is mg per day. This is taken as 75 mg twice per day. After 1 week, your doctor may increase your dosage to mg twice per day a total of mg per day.
Whether or not your dosage is increased will depend on how well the drug is working for you and any side effects that you may experience. This is the maximum dosage for treating fibromyalgia. The recommended starting dosage of Lyrica for adults with nerve pain after shingles is mg per day.
This can be taken as 75 mg twice per day or 50 mg three times per day. After 1 week, your doctor may increase your dosage to one of the two recommended dosages. Both options equal a total of mg to mg:. After 2 to 4 weeks of taking mg daily, your doctor may increase your dosage to the maximum of mg daily. This can either be taken as mg twice per day or mg three times per day. For treating nerve pain from a spinal cord injury , the recommended starting dosage of Lyrica is mg per day. This is taken either as 50 mg three times per day or 75 mg twice per day.
This is divided into two or three doses per day. For example, if a child weighs 32 kg about 70 pounds [lb] , the recommended starting dosage would be 80 mg total per day. This could be taken as 40 mg twice daily. It could also be split into three doses per day such as 30 mg in the morning and afternoon, and 20 mg at night. The maximum dosage for children in this weight range is 10 mg per kg of body weight daily, with a maximum of mg per day. This dosage should be divided into two or three doses per day.
For example, if a child weighs 20 kg about 44 lb , the recommended starting dosage would be 70 mg total per day. This could be taken as 35 mg twice per day. It could also be split into three doses per day such as 20 mg in the morning and afternoon, and 10 mg at night. The maximum dosage for children in this weight range is 14 mg per kg of body weight daily. For children ages 1 month to younger than 4 years, this should be divided into three doses per day. For children ages 4 years and older, this may be divided into two or three doses per day.
Then, take your next dose as its regular time. This could raise your risk for side effects. This can include setting an alarm on your phone or downloading a reminder app. A kitchen timer can also work. Lyrica is meant to be used as a long-term treatment.
You may wonder how Lyrica compares with other medications that are prescribed for similar uses. Here, we look at how Lyrica and gabapentin are alike and different. Lyrica belongs to a drug class called antiepileptic drugs AEDs.
Lyrica contains the active drug pregabalin. Gabapentin is also an AED. Gabapentin is approved for use in children ages 3 years and older.
But this form of Lyrica is only available in one strength: 20 mg of the drug per milliliter mL of liquid. Gabapentin comes in three forms: capsules, tablets, and a liquid solution. All are taken by mouth. Gabapentin is available in the following strengths:. Lyrica and gabapentin have some similar side effects and others that vary.
Below are examples of these side effects. These lists contain examples of serious side effects that can occur with either Lyrica or gabapentin, as well as serious side effects that both drugs may share. But studies have found both Lyrica and gabapentin to be effective for nerve pain after shingles and for partial onset seizures. According to estimates on GoodRx. Lyrica is a brand-name drug. Brand-name medications usually cost more than generics.
Gabapentin is a generic drug. Other drugs are available that can treat your condition. Some may be a better fit for you than others.
They can tell you about other medications that may work well for you. Note: Some of the drugs listed here are used off-label to treat these specific conditions. Examples of other drugs that may be used to treat diabetic nerve pain include:.
Examples of other drugs that may be used to treat fibromyalgia include:. Examples of other drugs that may be used to treat pain after shingles include:. Examples of other drugs that may be used to treat nerve pain from a spinal cord injury include:.
Examples of other drugs that may be used to treat partial onset seizures include:. In larger clinical studies :. Because of this, anyone with a history of misusing alcohol, prescription medications, or recreational drugs should talk with their doctor before using Lyrica.
It might. Lyrica can show up on certain drug tests that specifically screen for pregabalin, which is its active drug. Instead, most drug tests look for drugs that are commonly misused or used illegally, including:. Pregabalin belongs to a class of medications known as antiepileptic drugs. But Lyrica is a controlled substance. Anyone with a history of misusing drugs or alcohol may be more likely to misuse Lyrica.
If you have questions or concerns about misusing Lyrica, talk with your doctor before you start treatment. Lyrica may cause certain side effects that could affect your ability to drive or operate machinery. These side effects can include:. Yes, Lyrica can be used in people with diabetes. The drug is approved to treat diabetic nerve pain. But people with diabetes should pay special attention to their skin while taking Lyrica. In animal studies , Lyrica caused skin ulcers sores.
If you have diabetes and notice any sores or skin problems while taking Lyrica, talk with your doctor. Lyrica may not be safe for you if you use certain other medications called thiazolidinediones to treat diabetes. Examples of thiazolidinediones include pioglitazone Actos and rosiglitazone Avandia.
Lyrica and thiazolidinediones can both cause swelling in your feet, hands, and legs. But in some people with breathing problems, Lyrica may cause respiratory depression slow and shallow breathing.
This side effect can be life threatening. Lyrica can also cause respiratory depression if taken with other drugs that depress the central nervous system CNS , such as opioids. If you have a breathing problem or are taking a CNS depressant, talk with your doctor before you start treatment with Lyrica.
If you do take Lyrica, your doctor will likely have you and the people around you watch for sedation severe sleepiness or worsening breathing problems.
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